Nasal spray vaccine that stops heart attacks by cutting fat in arteries 'will be here

[lonster1]

Nasal spray vaccine that stops heart attacks by cutting fat in arteries 'will be here within five years'

A vaccine delivered in an injection or nasal spray to prevent heart attacks could be available within five years.

Scientists have discovered that the drug stimulates the body's immune system to produce antibodies which prevent heart disease by stopping fat building up in the arteries.

It is the first time that the underlying cause of heart disease has been targeted. Current treatments focus on using drugs to reduce cholesterol levels and blood pressure.

The vaccine can cut the build up of fat in arteries by up to 70 per cent, according to tests by researchers at Lund University in Sweden. The fatty deposits cause arteries to narrow, meaning the body has to work harder to pump blood, and can lead to a heart attack.

Prof Peter Weissberg, the British Heart Foundation medical director, said the vaccine was "very promising".

Different ways of administering the vaccine are being developed and could be licensed within five years, the Frontiers in CardioVascular Biology conference at Imperial College London was told.

Cardiovascular disease is the biggest killer in Britain, causing one in three deaths; 191,000 each year. There are 2.7?million people with heart disease and their treatment costs pounds 3.2?billion a year.

Prof Jan Nilsson, professor of experimental cardiovascular research at Lund University, acknowledged that treatments such as statins and blood pressure drugs reduced the risk of heart disease by 40 per cent, but added: "It should not be forgotten that 60 per cent of cardiovascular events continue to occur."

He said: "These treatments are far more like drugs: to be effective they'd need to be given long term. The antibody therapy in particularly is likely to be expensive, so you could probably only afford to give it to high-risk populations rather than everyone."

The team created a vaccine that reduced plaque build-up by 60 to 70 per cent in mice. The resulting injection is waiting regulatory clearance to start clinical trials. A second vaccine has been created as a nasal spray. A trial on 144 heart disease sufferers is under way in the U.S. and Canada.

[satchick]

We should be fixing the problem, not the symptom. I wonder what percentage of heart disease (especially in younger people) is caused by their own lifestyle choices? People just need to stop pumping their bodies full of garbage and chemicals. Just avoiding processed, fatty food that's full of preservatives and nothing more than empty calories with zero nutritional value will really reduce the risk of health problems in general, not just heart attacks. In addition to eating properly, getting enough exercise is really important too...

I can only see drugs like these being used as a free pass to continue to eat sh*tty food and sit around doing nothing...

[slugworth]

get out there and exercise instead of sitting all day.
when I was a kid I didn't know anybody that was fat or had allergies/syndromes.

[watox69]

its all the GMO foods and fluoride in the water along with the push of cancer filled vaccines.

[zhong]

So what are the side affects of this vaccine ? I guess we will see the trial results on the 144 guinea pigs.


Nasal spray vaccine that stops heart attacks by cutting fat in arteries 'will be here within five years'

A vaccine delivered in an injection or nasal spray to prevent heart attacks could be available within five years.

Scientists have discovered that the drug stimulates the body's immune system to produce antibodies which prevent heart disease by stopping fat building up in the arteries.

It is the first time that the underlying cause of heart disease has been targeted. Current treatments focus on using drugs to reduce cholesterol levels and blood pressure.

The vaccine can cut the build up of fat in arteries by up to 70 per cent, according to tests by researchers at Lund University in Sweden. The fatty deposits cause arteries to narrow, meaning the body has to work harder to pump blood, and can lead to a heart attack.

Prof Peter Weissberg, the British Heart Foundation medical director, said the vaccine was "very promising".

Different ways of administering the vaccine are being developed and could be licensed within five years, the Frontiers in CardioVascular Biology conference at Imperial College London was told.

Cardiovascular disease is the biggest killer in Britain, causing one in three deaths; 191,000 each year. There are 2.7?million people with heart disease and their treatment costs pounds 3.2?billion a year.

Prof Jan Nilsson, professor of experimental cardiovascular research at Lund University, acknowledged that treatments such as statins and blood pressure drugs reduced the risk of heart disease by 40 per cent, but added: "It should not be forgotten that 60 per cent of cardiovascular events continue to occur."

He said: "These treatments are far more like drugs: to be effective they'd need to be given long term. The antibody therapy in particularly is likely to be expensive, so you could probably only afford to give it to high-risk populations rather than everyone."

The team created a vaccine that reduced plaque build-up by 60 to 70 per cent in mice. The resulting injection is waiting regulatory clearance to start clinical trials. A second vaccine has been created as a nasal spray. A trial on 144 heart disease sufferers is under way in the U.S. and Canada.